Model Lineup
As before, the RX comes in two forms. The RX 350 is equipped with a traditional gasoline engine, while the RX 450h contains a hybrid (gasoline/electric) powertrain. Aluminum-alloy 18-inch wheels are standard on the RX 350, and 19-inch wheels come on the RX 450h. Hybrid models also have unique styling touches to set it apart, including a distinctive grille, hybrid badges, and blue-tinted headlamps and taillamps. LED taillamps are optional for the RX 450h.

Despite its premium status, Lexus's RX has a substantial options list, including Mark Levinson Surround Sound, dual-screen rear-seat entertainment, and dynamic radar cruise control. An optional Sports package provides a sport-tuned suspension. An available Hard Disk Drive navigation system includes a new "Remote Touch" controller on the center console, and is said to be as natural to use as a computer mouse. The controller may be customized to the driver's preferred level of feedback and new casual language voice recognition in the navigation system can respond to conversational commands. XM satellite radio compatibility is standard, now including XM NavTraffic and NavWeather features.

A wide-angle side-view monitor is new for 2010. A camera under the passenger-side mirror provides a display that lets the driver check hard-to-view areas, by selecting a button on the navigation screen or the steering wheel.